Corticosteroids

The chemical synthesis of naturally occurring corticosteroids has led to the generation of artificial corticosteroids that are used in therapeutic veterinary drugs.  Many of these drugs are also used as growth promoters particularly in cattle, often in combination with beta-agonists.  Dexamethasone, Flumethasone and Betamethasone all belong to this group of drugs that are also known as glucocorticosteriods. The European Union has banned the use of corticosteroids administration for fattening purposes in animals.

The Randox Food Diagnostics Corticosteroids ELISA test kit can be used to detect Dexamethasone, Flumethasone and Betamethasone within a urine sample.

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No of Tests

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DM2156

96 tests

1

POA

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Corticosteroids ELISA in Urine (IDM2156)

Assay

Compound

% Cross reactivity

LOD (ppb)

Dexamethasone

Dexamethasone

100

(Rapid screen ) 0.25
(IAC) 0.1

Dexamethasone 21 Acetate

162

Dexamethasone 21 Phospate

3.6

Flumethasone

Flumethasone

50

(Rapid screen ) 5.0
(IAC) 0.2

Betamethasone

Betamethasone

43

(Rapid screen ) 5.8
(IAC) 0.23

Betamethasone 21 Acetate

73

Betamethasone 21 Phosphate

2.0

Triamcionlone

1.0

Prednisolone

1.7

Cortisol

<0.5

Cortisone

<0.5

Multiple detection of compounds

  • Simultaneously screen for flumethasone, dexamethasone and betamethasone

Low cross-reactivity

  • Very low cross-reactivity for cortisol (<0.5%)

Exceptional limits of detection

  • Lower levels of detection, within government MRLs

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