Ketamine

This ELISA aims to give a fast, reliable, analytical method to detect the presence of ketamine. Ketamine was first synthesized in 1962 and subsequently marketed as an anaesthetic drug for human and animal use. It is a dissociative medical anaesthetic agent possessing hallucinogenic properties.

Ketamine became a drug of abuse shortly after it was introduced to clinical use. It has a very short half-life and rapid clearance from the body. It has been postulated that Ketamine is metabolised by N-demethylation, to yield the active metabolite norketamine, which is then followed by a hydroxylation process yielding hydroxyl-norketamine (HNK). The HNK can then undergo glucuronidation conjugation. It is thought that the norketamine can undergo dehydrogenation to yield dehydronorketamine.

The Randox Food Diagnostics Ketamine ELISA test kit has an excellent limit of detection of 4.54ng/ml for equine urine.

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KT3459

96 tests

1

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Ketamine ELISA

Assay

Compound

% Cross Reactivity

LOD (ppb)

Ketamine

Norketamine

100

Equine urine 4.54ng/ml

Ketamine

2.89

Dehydronorketamine

4.47

Exceptional limits of detection

  • LOD of 4.54ng/ml for equine urine

Various compounds from a single sample detected

  • Detects Norketamine and Dehydronorketamine

Plates pre-coated with analyte specific antibody

  • Reducing assay set up time

Rapid and simple assay format

  • 40 samples can be analysed in 90 mins, less labour
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